(Pro)renin receptor is component of the renin angiotensin system which has been shown to be involved in several physiological and pathophysiological processes including blood pressure regulation and hypertension, water and electrolyte balance, kidney injury, obesity, and metabolic dysfunction. Enzymatic cleavage of prorenin receptor produces soluble prorenin receptor which can also activate the renin angiotensin system stimulate similar pathophysiological process like its full form receptor. This review explores findings on the role of prorenin receptor and soluble prorenin receptor in metabolic dysfunction and discusses the conflicting findings on soluble prorenin receptor in metabolic dysfunction.
"(Pro)renin Receptor And Its Soluble Form in Metabolic Dysfunction: Friend or Foe?,"
Journal of Pharmacology & Nutritional Sciences: Vol. 1:
1, Article 1.
Available at: https://uknowledge.uky.edu/jpns/vol1/iss1/1