Year of Publication
A novel surface plasmon resonance sensor is fabricated to evaluate its use in biochemical sensing. The sensor can differentiate between bulk refractive index changes and surface binding reactions of interest. There has been a great interest in developing sensors to differentiate biological or chemical agents from interfering effects, but they still remain in research phase. In this work, a prism coupler is used to simultaneously excite both long and short range surface plasmon modes of the sensor. The differing sensitivities of the long and short range modes allow one to distinguish surface binding reactions of interest from refractive index fluctuations. In this thesis, we have demonstrated the sensors self referencing capability by detecting the formation of an octadecanethiol self assembled monolayer while varying solution refractive index.
Donipudi, Raghunandan K., "Self referencing SPR sensor by simultaneous excitation of long and short range surface plasmon modes" (2006). University of Kentucky Master's Theses. 274.