Alzheimer’s disease (AD) research progress is impeded due to participant recruitment challenges. This study seeks to better understand, from the perspective of individuals engaged in clinical trials (CTs), research motivations.


Participants, or their caregivers, from AD treatment and prevention CTs were surveyed about research motivators.


The 87 respondents had a mean age of 72.2, were predominantly Caucasian, 55.2% were male, and 56.3% had cognitive impairment. An overwhelming majority rated the potential to help themselves or a loved one and the potential to help others in the future as important motivators. Relatively few respondents were motivated by free healthcare, monetary rewards, or to make others happy.


Recruitment efforts should focus on the potential benefit for the individual, their loved ones, and others in the future rather than free healthcare or monetary rewards.

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Published in Aging Clinical and Experimental Research, v. 30, issue 2, p. 209-212.

© Springer International Publishing Switzerland 2017

The copyright holder has granted the permission for posting the article here.

This is a post-peer-review, pre-copyedit version of an article published in Aging Clinical and Experimental Research. The final authenticated version is available online at: https://doi.org/10.1007/s40520-017-0771-2.

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The data sets during and/or analyzed during the current study available from the corresponding author on reasonable request.