Abstract
Pulmonary hemorrhage after administration of tissue plasminogen activator (tPA) is a rare complication. We present a 15- year-old boy with a heterozygous pathogenic variant in ACTA2 who presented with right brachial artery aneurysm thrombosis treated initially with tPA, resulting in pulmonary hemorrhage. We hypothesize that the underlying pulmonary abnormalities caused by the pathogenic ACTA2 variant may be a risk factor for pulmonary hemorrhage after tPA administration. (J Vasc Surg Cases Innov Tech 2024;10:101558.)
Document Type
Article
Publication Date
12-2024
Digital Object Identifier (DOI)
https://doi.org/10.1016/j.jvscit.2024.101558
Repository Citation
Hughes, Travis G.; Wurth, Mark A.; and Sheppard, Mary Burchett, "Tissue plasminogen activator associated pulmonary hemorrhage in patient with ACTA2-associated arteriopathy" (2024). Saha Cardiovascular Research Center Faculty Publications. 60.
https://uknowledge.uky.edu/cvrc_facpub/60
Notes/Citation Information
© 2024 The Author(s)