The title compound, C20H23N3O6·CH3OH, was synthesized by [3 + 2] cyclo­addition of (Z)-2,3-bis­(3,4,5-tri­meth­oxy­phen­yl)acrylo­nitrile with sodium azide and ammonium chloride in DMF/water. The central nitro­gen of the triazole ring is protonated. The dihedral angles between the triazole ring and the 3,4,5-tri­meth­oxy­phenyl ring planes are 34.31 (4) and 45.03 (5)°, while that between the 3,4,5-tri­meth­oxy­phenyl rings is 51.87 (5)°. In the crystal, the mol­ecules, along with two methanol solvent mol­ecules are linked into an R 4 4(10) centrosymmetric dimer by N—H⋯O and O—H⋯N hydrogen bonds.

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Published in Acta Crystallographica Section E: Crystallographic Communications, v. 70, part 10, p. o1128-o1129.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.

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This investigation was supported NIH/National Cancer Institute (CA140409) United States, and we also thank the Arkansas Research Alliance for financial support.

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Supporting information for this paper is available from the IUCr electronic archives (Reference: SJ5427).

CCDC reference: 1025101

Crystal structure: contains datablocks global, I. DOI: 10.1107/S1600536814020911/sj5427sup1.cif

Structure factors: contains datablock I. DOI: 10.1107/S1600536814020911/sj5427Isup2.hkl

Supporting information file. DOI: 10.1107/S1600536814020911/sj5427Isup3.cml

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sj5427.pptx (167 kB)
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sj5427sup1.cif (846 kB)
Crystal structure: contains datablocks global, I.

sj5427Isup2.hkl (267 kB)
Structure factors: contains datablock I.

sj5427Isup3.cml (8 kB)
Supporting information file.

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Supporting figures: Fig. 1.

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