Making of Viral Replication Organelles by Remodeling Interior Membranes
Abstract
Positive-stranded RNA (+RNA) viruses exploit host cell machinery by subverting host proteins and membranes and altering cellular pathways during infection. To achieve robust replication, some +RNA viruses, such as poliovirus (PV), build special intracellular compartments, called viral replication organelles. A recent work from the Altan-Bonnett laboratory [1] gave new insights into the formation of poliovirus replication organelles, which are unique subcellular structures containing many individual replication complexes as a result of dynamic cellular membrane remodeling.
Document Type
Article
Publication Date
Winter 11-5-2010
Digital Object Identifier (DOI)
10.3390/v2112436
Repository Citation
Nagy, Peter D. and Sasvari, Zsuzsanna, "Making of Viral Replication Organelles by Remodeling Interior Membranes" (2010). Faculty Publications. 6.
https://uknowledge.uky.edu/all_facpub/6
