This collection was named as Graduate Center for Toxicology Faculty Publications before Jan. 1, 2015.

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Submissions from 2017

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Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis, Ravshan Burikhanov, Nikhil Hebbar, Sunil K. Noothi, Nidhi Shukla, James Sledziona, Nathália Araujo, Meghana Kudrimoti, Qing Jun Wang, David S. Watt, Danny R. Welch, Jodi Maranchie, Akihiro Harada, and Vivek M. Rangnekar

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Lkb1 Inactivation Drives Lung Cancer Lineage Switching Governed by Polycomb Repressive Complex 2, Haikuo Zhang, Christine Fillmore Brainson, Shohei Koyama, Amanda J. Redig, Ting Chen, Shuai Li, Manav Gupta, Carolina Garcia-de-Alba, Margherita Paschini, Grit S. Herter-Sprie, Gang Lu, Xin Zhang, Bryan P. Marsh, Stephanie J. Tuminello, Chunxiao Xu, Zhao Chen, Xiaoen Wang, Esra A. Akbay, Mei Zheng, Sangeetha Palakurthi, Lynette M. Sholl, Anil K. Rustgi, David J. Kwiatkowski, J. Alan Diehl, Adam J. Bass, Norman E. Sharpless, Glenn Dranoff, Peter S. Hammerman, Hongbin Ji, Nabeel Bardeesy, Dieter Saur, Hideo Watanabe, Carla F. Kim, and Kwok-Kin Wong

Submissions from 2016

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Dasatinib-loaded Albumin Nanoparticles Possess Diminished Endothelial Cell Barrier Disruption and Retain Potent Anti-Leukemia Cell Activity, Chunling Dong, Bo Li, Zhenyu Li, Sreerama Shetty, and Jian Fu

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Stable Isotope Resolved Metabolomics Studies in ex vivo Tissue Slices, Teresa W-M Fan, Andrew N. Lane, and Richard M. Higashi

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Exposure of Human Lung Cells to Tobacco Smoke Condensate Inhibits the Nucleotide Excision Repair Pathway, Nathaniel C. Holcomb, Mamta Goswami, Sung Gu Han, Samuel Clark, David K. Orren, C. Gary Gairola, and Isabel Mellon

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Melanocortin 1 Receptor: Structure, Function, and Regulation, Erin M. Wolf Horrell, Mary C. Boulanger, and John A. D'Orazio

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Changes in Mitochondrial Homeostasis and Redox Status in Astronauts Following Long Stays in Space, Hiroko P. Indo, Hideyuki J. Majima, Masahiro Terada, Shigeaki Suenaga, Kazuo Tomita, Shin Yamada, Akira Higashibata, Noriaki Ishioka, Takuro Kanekura, Ikuya Nonaka, Clare L. Hawkins, Michael J. Davies, Daret K. St Clair, and Chiaki Mukai

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AKAP12 Mediates PKA-Induced Phosphorylation of ATR to Enhance Nucleotide Excision Repair, Stuart G. Jarrett, Erin M. Wolf Horrell, and John A. D'Orazio

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The Nobel Prize in Chemistry 2015: Exciting Discoveries in DNA Repair by Aziz Sancar, David K. Orren

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Hexavalent Chromium Induces Malignant Transformation of Human Lung Bronchial Epithelial Cells Via ROS-Dependent Activation of miR-21-PDCD4 Signaling, Poyil Pratheeshkumar, Young-Ok Son, Sasidharan Padmaja Divya, Lilia Turcios, Ram Vinod Roy, John Andrew Hitron, Lei Wang, Donghern Kim, Jin Dai, Padmaja Asha, Zhuo Zhang, and Xianglin Shi

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Quercetin Inhibits Cr(VI)-Induced Malignant Cell Transformation by Targeting miR-21-PDCD4 Signaling Pathway, Poyil Pratheeshkumar, Young-Ok Son, Sasidharan Padmaja Divya, Lei Wang, Lilia Turcios, Ram Vinod Roy, John Andrew Hitron, Donghern Kim, Jin Dai, Padmaja Asha, Zhuo Zhang, and Xianglin Shi

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Oncogenic Transformation of Human Lung Bronchial Epithelial Cells Induced by Arsenic Involves ROS-Dependent Activation of STAT3-miR-21-PDCD4 Mechanism, Poyil Pratheeshkumar, Young-Ok Son, Sasidharan Padmaja Divya, Lei Wang, Zhuo Zhang, and Xianglin Shi

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S100A4 Drives Non-Small Cell Lung Cancer Invasion, Associates with Poor Prognosis, and is Effectively Targeted by the FDA-Approved Anti-Helminthic Agent Niclosamide, Rachel L. Stewart, Brittany L. Carpenter, Dava S. West, Teresa Knifley, Lili Liu, Chi Wang, Heidi L. Weiss, Tamas S. Gal, Eric B. Durbin, Susanne M. Arnold, Kathleen L. O'Connor, and Min Chen

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Metabolomics Workbench: An International Repository for Metabolomics Data and Metadata, Metabolite Standards, Protocols, Tutorials and Training, and Analysis Tools, Manish Sud, Eoin Fahy, Dawn Cotter, Kenan Azam, Ilango Vadivelu, Charles Burant, Arthur Edison, Oliver Fiehn, Richard M. Higashi, K. Sreekumaran Nair, Susan Sumner, and Shankar Subramaniam

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Analysis of RNA Expression of Normal and Cancer Tissues Reveals High Correlation of COP9 Gene Expression with Respiratory Chain Complex Components, Christina A. Wicker and Tadahide Izumi

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ErbB2 and p38γ MAPK Mediate Alcohol-Induced Increase in Breast Cancer Stem Cells and Metastasis, Mei Xu, Zhenhua Ren, Xin Wang, Ashley Comer, Jacqueline A. Frank, Zun-Ji Ke, Yi Huang, Zhuo Zhang, Xianglin Shi, Siying Wang, and Jia Luo

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Physicochemical Properties of Engineered Nanomaterials that Influence Their Nervous System Distribution and Effects, Robert A. Yokel

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Aluminum and Phthalates in Calcium Gluconate; Contribution from Glass and Plastic Packaging, Robert A. Yokel and Jason M. Unrine

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HDAC6 Inhibition Prevents TNF-α-Induced Caspase 3 Activation in Lung Endothelial Cell and Maintains Cell-Cell Junctions, Jinyan Yu, Mengshi Ma, Zhongsen Ma, and Jian Fu

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H2AX Deficiency is Associated with Erythroid Dysplasia and Compromised Haematopoietic Stem Cell Function, Baobing Zhao, Timothy L. Tan, Yang Mei, Jing Yang, Yiting Yu, Amit Verma, Ying Liang, Juehua Gao, and Peng Ji

Submissions from 2015

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Integrin α6β4 Promotes Autocrine Epidermal Growth Factor Receptor (EGFR) Signaling to Stimulate Migration and Invasion toward Hepatocyte Growth Factor (HGF), Brittany L. Carpenter, Min Chen, Teresa Knifley, Kelley A. Davis, Susan M.W. Harrison, Rachel L. Stewart, and Kathleen O'Connor

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Alternating Magnetic Field-Induced Hyperthermia Increases Iron Oxide Nanoparticle Cell Association/Uptake and Flux in Blood-Brain Barrier Models, Mo Dan, Younsoo Bae, Thomas A. Pittman, and Robert A. Yokel

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The DNA Structure and Sequence Preferences of WRN Underlie Its Function in Telomeric Recombination Events, Deanna N. Edwards, Amrita Machwe, Li Chen, Vilhelm A. Bohr, and David K. Orren

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Plasma TNF-α and Soluble TNF Receptor Levels after Doxorubicin with or without Co-Administration of Mesna-A Randomized, Cross-Over Clinical Study, John Hayslip, Emily Van Meter Dressler, Heidi L. Weiss, Tammy J. Taylor, Mara D. Chambers, Teresa Noel, Sumitra Miriyala, Jeriel T. R. Keeney, Xiaojia Ren, Rukhsana Sultana, Mary Vore, D. Allan Butterfield, Daret St. Clair, and Jeffrey A. Moscow

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The C-terminal Domain (CTD) of Human DNA GlycosylaseNEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome: DOMINANT NEGATIVE FUNCTION OF THE CTD, Pavana M. Hegde, Arijit Dutta, Shiladitya Sengupta, Joy Mitra, Sanjay Adhikari, Alan E. Tomkinson, Guo-Min Li, Istvan Boldogh, Tapas K. Hazra, Sankar Mitra, and Muralidhar L. Hegde