US Patent Number
The presently-disclosed subject matter provides methods for preventing ischemia in a cell, treating ischemia in a subject, and preventing an infarction in a subject that utilize α5β1 integrin inhibitor. In some instances, α5β1 integrin inhibitor is administered to a subject prior to, during, or after the onset of ischemia to treat the ischemia and/or prevent infarction. In some instances the present methods prevent the occurrence of an infarction. In some instances the present methods restores perfusion to organs and tissues.
University of Kentucky Research Foundation, Lexington, Ky
Bix, Gregory J., "Compositions and Methods for Treating Ischemia" (2016). Sanders-Brown Center on Aging Faculty Patents. 4.