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Submissions from 2016

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A Branch Point of Streptomyces Sulfur Amino Acid Metabolism Controls the Production of Albomycin, Aditya Kulkarni, Yu Zeng, Wei Zhou, Steven Van Lanen, Weiwen Zhang, and Shawn Chen

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Physicochemical Properties of Engineered Nanomaterials that Influence Their Nervous System Distribution and Effects, Robert A. Yokel

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Aluminum and Phthalates in Calcium Gluconate; Contribution from Glass and Plastic Packaging, Robert A. Yokel and Jason M. Unrine

Submissions from 2015

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The Biosynthesis of Capuramycin-type Antibiotics: Identification of the A-102395 Biosynthetic Gene Cluster, Mechanism of Self-Resistence, and Formation of Uridine-5'-Carboxamide, Wenlong Cai, Anwesha Goswami, Zhaoyong Yang, Xiaodong Liu, Keith D. Green, Sandra Barnard-Britson, Satoshi Baba, Masanori Funabashi, Koichi Nonaka, Manjula Sunkara, Andrew J. Morris, Anatol P. Spork, Christian Ducho, Sylvie Garneau-Tsodikova, Jon S. Thorson, and Steven Van Lanen

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FRET Detection of Lymphocyte Function-Associated Antigen-1 Conformational Extension, Alexandre Chigaev, Yelena Smagley, Mark K. Haynes, Oleg Ursu, Cristian G. Bologa, Liliana Halip, Tudor Oprea, Anna Waller, Mark B. Carter, Yinan Zhang, Wei Wang, Tione Buranda, and Larry A. Sklar

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Regression of Gastric Cancer by Systemic Injection of RNA Nanoparticles Carrying Both Ligand and siRNA, Daxiang Cui, Chunlei Zhang, Bing Liu, Yi Shu, Tong Du, Dan Shu, Kan Wang, Fangping Dai, Yanlei Liu, Chao Li, Fei Pan, Yuming Yang, Jian Ni, Hui Li, Beate Brand-Saberi, and Peixuan Guo

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Alternating Magnetic Field-Induced Hyperthermia Increases Iron Oxide Nanoparticle Cell Association/Uptake and Flux in Blood-Brain Barrier Models, Mo Dan, Younsoo Bae, Thomas A. Pittman, and Robert A. Yokel

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Derivation of an Analytical Solution to a Reaction-Diffusion Model for Autocatalytic Degradation and Erosion in Polymer Microspheres, Ashlee N. Ford Versypt, Paul D. Arendt, Daniel W. Pack, and Richard D. Braatz

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Pharmacologically Distinct Nicotinic Acetylcholine Receptors Drive Efferent-Mediated Excitation in Calyx-Bearing Vestibular Afferents, J. Chris Holt, Kevin Kewin, Paivi M. Jordan, Peter Cameron, Marcin Klapczynski, J. Michael McIntosh, Peter A. Crooks, Linda P. Dwoskin, and Anna Lysakowski

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Drug Synergy Drives Conserved Pathways to Increase Fission Yeast Lifespan, Xinhe Huang, Markos Leggas, and Robert C. Dickson

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An in Vitro Assessment of Liposomal Topotecan Simulating Metronomic Chemotherapy in Combination with Radiation in Tumor-Endothelial Spheroids, Amar Jyoti, Kyle Daniel Fugit, Pallavi Sethi, Ronald C. McGarry, Bradley D. Anderson, and Meenakshi Upreti

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RNA Nanoparticle as a Vector for Targeted siRNA Delivery into Glioblastoma Mouse Model, Tae Jin Lee, Farzin Haque, Dan Shu, Ji Young Yoo, Hui Li, Robert A. Yokel, Craig Horbinski, Tae Hyong Kim, Sung-Hak Kim, Chang-Hyuk Kwon, Ichiro Nakano, Balveen Kaur, Peixuan Guo, and Carlo M. Croce

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Inhibition of Aminoglycoside Acetyltransferase Resistance Enzymes by Metal Salts, Yijia Li, Keith D. Green, Brooke R. Johnson, and Sylvie Garneau-Tsodikova

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Pharmacology: The Pharmacodynamics of Nutrients and Nutrient Interactions in Biological Functions, M. Hasan Mohajeri, Gunter P. Eckert, James R. Pauly, and Christopher M. Butt

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A Combination Approach to Treating Fungal Infections, Sanjib K. Shrestha, Marina Y. Fosso, and Sylvie Garneau-Tsodikova

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Amphiphilic Tobramycin Analogues as Antibacterial and Antifungal Agents, Sanjib K. Shrestha, Marina Y. Fosso, Keith D. Green, and Sylvie Garneau-Tsodikova

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New Approach to Develop Ultra-High Inhibitory Drug Using the Power Function of the Stoichiometry of the Targeted Nanomachine or Biocomplex, Dan Shu, Fengmei Pi, Chi Wang, Peng Zhang, and Peixuan Guo

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Crystal Structure of O-Methyltransferase CalO6 from the Calicheamicin Biosynthetic Pathway: A Case of Challenging Structure Determination at Low Resolution, Oleg V. Tsodikov, Caixia Hou, Christopher T. Walsh, and Sylvie Garneau-Tsodikova

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Chemically Related 4,5-Linked Aminoglycoside Antibiotics Drive Subunit Rotation in Opposite Directions, Michael R. Wasserman, Arto Pulk, Zhou Zhou, Roger B. Altman, John C. Zinder, Keith D. Green, Sylvie Garneau-Tsodikova, Jamie H. Doudna Cate, and Scott C. Blanchard

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Influence of Linker Length and Composition on Enzymatic Activity and Ribosomal Binding of Neomycin Dimers, Derrick Watkins, Sunil Kumar, Keith D. Green, Dev P. Arya, and Sylvie Garneau-Tsodikova

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Factors Affecting the Pharmacokinetics and Pharmacodynamics of PEGylated Liposomal Irinotecan (IHL-305) in Patients with Advanced Solid Tumors, Huali Wu, Jeffrey R. Infante, Vicki L. Keedy, Suzanne F. Jones, Emily Chan, Johanna C. Bendell, Wooin Lee, Whitney P. Kirschbrown, Beth A. Zamboni, Satoshi Ikeda, Hiroshi Kodaira, Mace L. Rothenberg, Howard A. Burris, and William C. Zamboni

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Silver Nanoparticles Induce Tight Junction Disruption and Astrocyte Neurotoxicity in a Rat Blood-Brain Barrier Primary Triple Coculture Model, Liming Xu, Mo Dan, Anliang Shao, Xiang Cheng, Cuiping Zhang, Robert A. Yokel, Taro Takemura, Nobutaka Hanagata, Masami Niwa, and Daisuke Watanabe

Submissions from 2014

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Finding of Widespread Viral and Bacterial Revolution dsDNA Translocation Motors Distinct from Rotation Motors by Channel Chirality and Size, Gian Marco De-Donatis, Zhengyi Zhao, Shaoying Wang, Lisa P. Huang, Chad T. Schwartz, Oleg V. Tsodikov, Hui Zhang, Farzin Haque, and Peixuan Guo

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IVIVC from Long Acting Olanzapine Microspheres, Susan D'Souza, Jabar A. Faraj, Stefano Giovagnoli, and Patrick P. DeLuca

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Effects of Three Low-Doses of D-Tagatose on Glycemic Control Over Six Months in Subjects with Mild Type 2 Diabetes Mellitus Under Control with Diet and Exercise, Mark Ensor, Jarrod Williams, Rebecca Smith, Amy Banfield, and Robert A. Lodder