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Theses/Dissertations from 2014

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MECHANISMS OF CYCLOOXYGENASE-2-DEPENDENT HUMAN AORTIC SMOOTH MUSCLE CELL PHENOTYPIC MODULATION, Oreoluwa O. Adedoyin

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LOBELANE ANALOGS WITH VARIOUS METHYLENE LINKER LENGTHS AND ACYCLIC LOBELANE ANALOGS AS POTENTIAL PHARMACOTHERAPIES TO TREAT METHAMPHETAMINE ABUSE, Zheng Cao

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INVESTIGATING STRUCTURE AND PROTEIN-PROTEIN INTERACTIONS OF KEY POST-TYPE II PKS TAILORING ENZYMES, Theresa E. Downey

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QUANTIFICATION OF FACTORS GOVERNING DRUG RELEASE KINETICS FROM NANOPARTICLES: A COMBINED EXPERIMENTAL AND MECHANISTIC MODELING APPROACH, Kyle Daniel Fugit

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HUMAN BUTYRYLCHOLINESTERASE MUTANTS FOR COCAINE DETOXIFICATION, Shurong Hou

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MULTI-COMPONENT MICROPARTICULATE/NANOPARTICULATE DRY POWDER INHALATION AEROSOLS FOR TARGETED PULMONARY DELIVERY, Xiaojian Li

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THE OFF-LABEL USE OF ATYPICAL ANTIPSYCHOTICS AND ITS IMPACT ON ATTENTION DEFICIT/HYPERACTIVITY DISORDER (ADHD), Minji Sohn

Theses/Dissertations from 2013

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HIGH DOSE SIMVASTATIN AS A POTENTIAL ANTICANCER THERAPY IN LEUKEMIA PATIENTS, Tamer Ahmed

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Amalgamation of Nucleosides and Amino Acids in Antibiotic Biosynthesis, Sandra H. Barnard

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BIOSYNTHETIC PATHWAY OF THE AMINORIBOSYL COMPONENT OF LIPOPEPTIDYL NUCLEOSIDE ANTIBIOTICS, Xiuling Chi

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THE PHARMACOKINETICS OF METAL-BASED ENGINEERED NANOMATERIALS, FOCUSING ON THE BLOOD-BRAIN BARRIER, Mo Dan

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SYNTHESIS AND STABILITY STUDIES OF PRODRUGS AND CODRUGS OF NALTREXONE AND 6-β-NALTREXOL, Joshua A. Eldridge

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COMPUTATIONAL MODELING, DESIGN, AND CHARACTERIZATION OF COCAINE-METABOLIZING ENZYMES FOR ANTI-COCAINE MEDICATION, Lei Fang

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Formulation Optimization for Pore Lifetime Enhancement and Sustained Drug Delivery Across Microneedle Treated Skin, Priyanka Ghosh

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PRECLINICAL DEVELOPMENT OF PHYTOCANNABINOID- AND ENDOCANNABINOID- BASED PHARMACOTHERAPIES FOR THE TREATMENT OF ETHANOL-INDUCED NEURODEGENERATION, Daniel J. Liput

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MICROGLIA ACTIVATION IN A RODENT MODEL OF AN ALCOHOL USE DISORDER: THE IMPORTANCE OF PHENOTYPE, INITIATION, AND DURATION OF ACTIVATION, Simon A. Marshall

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The Critical Role of Mechanism-Based Models for Understanding and Predicting Liposomal Drug Loading, Binding and Release Kinetics, Sweta Modi

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DIET-INDUCED OBESITY: DOPAMINERGIC AND BEHAVIORAL MECHANISMS AS OUTCOMES AND PREDICTORS, Vidya Narayanaswami

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POLYMER MICELLES FOR TUNABLE DRUG RELEASE AND ENHANCED ANTITUMOR EFFICACY, Andrei G. Ponta

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Towards Elucidation of a Viral DNA Packaging Motor, Chad T. Schwartz

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METHYLPHENIDATE AND ATOMOXETINE TREATMENT DURING ADOLESCENCE IN THE SPONTANEOUSLY HYPERTENSIVE RAT: MECHANISMS UNDERLYING HIGH COCAINE ABUSE LIABILITY IN ATTENTION DEFICIT/HYPERACTIVITY DISORDER, Sucharita S. Somkuwar

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INVESTIGATING KEY POST-PKS ENZYMES FROM GILVOCARCIN BIOSYNTHETIC PATHWAY, Nidhi Tibrewal

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PRECLINICAL AND CLINICAL DEVELOPMENT OF THE LIPOPHILIC CAMPTOTHECIN ANALOGUE AR-67, Eleftheria Tsakalozou

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HIGH-ACTIVITY MUTANTS OF HUMAN BUTYRYLCHOLINESTERASE FOR COCAINE ABUSE TREATMENT, Liu Xue

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Expression of RNA Nanoparticles Based on Bacteriophage Phi29 pRNA in Escherichia coli and Bacillus subtilis, Le Zhang