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Theses/Dissertations from 2016

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Thermodynamics and Kinetics of the Three-Way Junction of Phi29 Motor pRNA and its Assembly into Nanoparticles for Therapeutic Delivery to Prostate Cancer, Daniel W. Binzel

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VENA CAVA FILTER UTILIZATION AND RETRIEVAL: A QUALITY OF CARE ISSUE, Joshua Brown

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Elucidating Proteasome Catalytic Subunit Composition and Its Role in Proteasome Inhibitor Resistance, Kimberly C. Carmony

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DEVELOPMENT OF COCAINE HYDROLASE FOR THERAPEUTIC TREATMENT OF COCAINE ABUSE, Xiabin Chen

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THE EFFECT OF NICOTINE CO-ADMINISTRATION ON ALCOHOL-INDUCED REACTIVE HIPPOCAMPAL CELL PROLIFERATION DURING ABSTINENCE IN AN ADOLESCENT MODEL OF AN ALCOHOL USE DISORDER, Megan Heath

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ANALYSIS OF KENTUCKY MEDICAID MANAGED CARE VERSUS FEE-FOR-SERVICE SYSTEMS: MEDICATION ADHERENCE IN PATIENTS WITH PREVALENT CHRONIC DISEASES, Catherine K. Herren

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IN VITRO ACTIVITY OF POLYMYXIN B AND MEROPENEM ALONE AND IN COMBINATION AGAINST CARBAPENEM-RESISTANT ENTEROBACTERIACEAE, Brandon T. Kulengowski

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RNA AS A UNIQUE POLYMER TO BUILD CONTROLLABLE NANOSTRUCTURES FOR NANOMEDICINE AND NANOTECHNOLOGY, Hui Li

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Probing the Functional Relevance of Reactive Hippocampal Neurogenesis in a Model of an Alcohol Use Disorder, Chelsea Rhea Geil Nickell

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RNA Nanotechnology for Next Generation Targeted Drug Delivery, Fengmei Pi

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ACUTE KIDNEY INJURY IN PATIENTS TREATED WITH VANCOMYCIN AND PIPERACILLIN-TAZOBACTAM: A RETROSPECTIVE COHORT ANALYSIS, Wilbur Cliff Rutter

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CLINICAL OUTCOMES ASSOCIATED WITH TIME TO ANTIMICROBIAL THERAPY CHANGE FROM VANCOMYCIN TO DAPTOMYCIN IN STAPHYLOCOCCAL BACTEREMIA, Sarah J. Tennant

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Development of New Biological Nanopores and Their Application for Biosensing and Disease Detection, Shaoying Wang

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TOWARDS ELUCIDATION OF THE MECHANISM OF BIOLOGICAL NANOMOTORS, Zhengyi Zhao

Theses/Dissertations from 2015

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ANTIBIOTICS TARGETING TUBERCULOSIS: BIOSYNTHESIS OF A-102395 AND DISCOVERY OF NOVEL ACTINOMYCINS, Wenlong Cai

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Chemoenzymatic Studies to Enhance the Chemical Space of Natural Products, Jhong-Min Chen

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DESIGN, SYNTHESIS, AND PHARMACOLOGICAL EVALUATION OF THREE SERIES OF LOBELANE ANALOGS AS INHIBITORS OF THE VESICULAR MONOAMINE TRANSPORTER (VMAT2), John P. Culver

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ELUCIDATING THE MECHANISM OF LIPL: A NON-HEME FE(II), α -KETOGLUTARATE: URIDINE-5’-MONOPHOSPHATE DIOXYGENASE, Anwesha Goswami

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KINETICS AND MECHANISMS OF CRYSTAL GROWTH INHIBITION OF INDOMETHACIN BY MODEL PRECIPITATION INHIBITORS, Dhaval D. Patel

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MOLECULAR AND FUNCTIONAL INVESTIGATION OF CANCER-TYPE AND LIVER-TYPE VARIANTS OF ORGANIC ANION TRANSPORTING POLYPEPTIDE 1B3, Nilay Thakkar

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ROLES OF ABCG5 ABCG8 CHOLESTEROL TRANSPORTER IN LIPID HOMEOSTASIS, Yuhuan Wang

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Medication misadventures: the case of benzodiazepines, Sarah E. Wixson

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A Molecular-Level View of the Physical Stability of Amorphous Solid Dispersions, Xiaoda Yuan

Theses/Dissertations from 2014

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MECHANISMS OF CYCLOOXYGENASE-2-DEPENDENT HUMAN AORTIC SMOOTH MUSCLE CELL PHENOTYPIC MODULATION, Oreoluwa O. Adedoyin

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LOBELANE ANALOGS WITH VARIOUS METHYLENE LINKER LENGTHS AND ACYCLIC LOBELANE ANALOGS AS POTENTIAL PHARMACOTHERAPIES TO TREAT METHAMPHETAMINE ABUSE, Zheng Cao