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Theses/Dissertations from 2015

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Chemoenzymatic Studies to Enhance the Chemical Space of Natural Products, Jhong-Min Chen

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DESIGN, SYNTHESIS, AND PHARMACOLOGICAL EVALUATION OF THREE SERIES OF LOBELANE ANALOGS AS INHIBITORS OF THE VESICULAR MONOAMINE TRANSPORTER (VMAT2), John P. Culver

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ELUCIDATING THE MECHANISM OF LIPL: A NON-HEME FE(II), α -KETOGLUTARATE: URIDINE-5’-MONOPHOSPHATE DIOXYGENASE, Anwesha Goswami

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KINETICS AND MECHANISMS OF CRYSTAL GROWTH INHIBITION OF INDOMETHACIN BY MODEL PRECIPITATION INHIBITORS, Dhaval D. Patel

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MOLECULAR AND FUNCTIONAL INVESTIGATION OF CANCER-TYPE AND LIVER-TYPE VARIANTS OF ORGANIC ANION TRANSPORTING POLYPEPTIDE 1B3, Nilay Thakkar

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ROLES OF ABCG5 ABCG8 CHOLESTEROL TRANSPORTER IN LIPID HOMEOSTASIS, Yuhuan Wang

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Medication misadventures: the case of benzodiazepines, Sarah E. Wixson

Theses/Dissertations from 2014

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MECHANISMS OF CYCLOOXYGENASE-2-DEPENDENT HUMAN AORTIC SMOOTH MUSCLE CELL PHENOTYPIC MODULATION, Oreoluwa O. Adedoyin

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LOBELANE ANALOGS WITH VARIOUS METHYLENE LINKER LENGTHS AND ACYCLIC LOBELANE ANALOGS AS POTENTIAL PHARMACOTHERAPIES TO TREAT METHAMPHETAMINE ABUSE, Zheng Cao

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INVESTIGATING STRUCTURE AND PROTEIN-PROTEIN INTERACTIONS OF KEY POST-TYPE II PKS TAILORING ENZYMES, Theresa E. Downey

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QUANTIFICATION OF FACTORS GOVERNING DRUG RELEASE KINETICS FROM NANOPARTICLES: A COMBINED EXPERIMENTAL AND MECHANISTIC MODELING APPROACH, Kyle Daniel Fugit

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HUMAN BUTYRYLCHOLINESTERASE MUTANTS FOR COCAINE DETOXIFICATION, Shurong Hou

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BEYOND PEROXISOME: ABCD2 MODIFIES PPARα SIGNALING AND IDENTIFIES A SUBCLASS OF PEROXISOMES IN MOUSE ADIPOSE TISSUE, Xiaoxi Liu

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MULTI-COMPONENT MICROPARTICULATE/NANOPARTICULATE DRY POWDER INHALATION AEROSOLS FOR TARGETED PULMONARY DELIVERY, Xiaojian Li

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Flavonoids with Novel Nicotinic Activity as Potential Pharmacotherapies to Treat Ethanol-Induced Neurotoxicity, Joseph A. Lutz

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Synthesis and Biological Evaluation of Novel Resveratrol and Combretastatin A4 Derivatives as Potent Anti-Cancer Agents, Nikhil Reddy Madadi

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THE OFF-LABEL USE OF ATYPICAL ANTIPSYCHOTICS AND ITS IMPACT ON ATTENTION DEFICIT/HYPERACTIVITY DISORDER (ADHD), Minji Sohn

Theses/Dissertations from 2013

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HIGH DOSE SIMVASTATIN AS A POTENTIAL ANTICANCER THERAPY IN LEUKEMIA PATIENTS, Tamer Ahmed

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Amalgamation of Nucleosides and Amino Acids in Antibiotic Biosynthesis, Sandra H. Barnard

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BIOSYNTHETIC PATHWAY OF THE AMINORIBOSYL COMPONENT OF LIPOPEPTIDYL NUCLEOSIDE ANTIBIOTICS, Xiuling Chi

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THE PHARMACOKINETICS OF METAL-BASED ENGINEERED NANOMATERIALS, FOCUSING ON THE BLOOD-BRAIN BARRIER, Mo Dan

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SYNTHESIS AND STABILITY STUDIES OF PRODRUGS AND CODRUGS OF NALTREXONE AND 6-β-NALTREXOL, Joshua A. Eldridge

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COMPUTATIONAL MODELING, DESIGN, AND CHARACTERIZATION OF COCAINE-METABOLIZING ENZYMES FOR ANTI-COCAINE MEDICATION, Lei Fang

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Formulation Optimization for Pore Lifetime Enhancement and Sustained Drug Delivery Across Microneedle Treated Skin, Priyanka Ghosh

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PRECLINICAL DEVELOPMENT OF PHYTOCANNABINOID- AND ENDOCANNABINOID- BASED PHARMACOTHERAPIES FOR THE TREATMENT OF ETHANOL-INDUCED NEURODEGENERATION, Daniel J. Liput