This collection was formerly known as Molecular and Biomedical Pharmacology Faculty Publications.

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Submissions from 2015

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Effects of Adipocyte Aryl Hydrocarbon Receptor Deficiency on PCB-Induced Disruption of Glucose Homeostasis in Lean and Obese Mice, Nicki A. Baker, Robin Shoemaker, Victoria English, Nika Larian, Manjula Sunkara, Andrew J. Morris, Mary Walker, Frederique Yiannikouris, and Lisa A. Cassis

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Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus, John C. Gant, Kuey-Chu Chen, Inga Kadish, Eric M. Blalock, Olivier Thibault, Nada M. Porter, and Philip W. Landfield

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PP2A Inhibitors Arrest G2/M Transition Through JNK/Sp1-Dependent Down-Regulation of CDK1 and Autophagy-Dependent Up-Regulation of p21, Fei-Ran Gong, Meng-Yao Wu, Meng Shen, Qiaoming Zhi, Ze-Kuan Xu, Rong Wang, Wen-Jie Wang, Yang Zong, Zeng-Liang Li, Yadi Wu, Binhua P. Zhou, Kai Chen, Min Tao, and Wei Li

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Early Shifts of Brain Metabolism by Caloric Restriction Preserve White Matter Integrity and Long-Term Memory in Aging Mice, Janet Guo, Vikas Bakshi, and Ai-Ling Lin

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Intracellular Na+ Concentration ([Na+]i) Is Elevated in Diabetic Hearts Due to Enhanced Na+–Glucose Cotransport, Rebekah Lambert, Sarah Srodulski, Xiaoli Peng, Kenneth B. Margulies, Florin Despa, and Sanda Despa

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Angiotensin II is Required to Induce Exaggerated Salt Sensitivity in Dahl Rats Exposed to Maternal Separation, Analia S. Loria, David M. Pollock, and Jennifer S. Pollock

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Thrombospondin1 Deficiency Attenuates Obesity-Associated Microvascular Complications in ApoE-/- Mice, Hasiyeti Maimaitiyiming, Kate Clemons, Qi Zhou, Heather Norman, and Shuxia Wang

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CD47 Deficiency Protects Mice from Diet-Induced Obesity and Improves Whole Body Glucose Tolerance and Insulin Sensitivity, Hasiyeti Maimaitiyiming, Heather Norman, Qi Zhou, and Shuxia Wang

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Inorganic Arsenic-Induced Cellular Transformation is Coupled with Genome Wide Changes in Chromatin Structure, Transcriptome and Splicing Patterns, Caitlyn Riedmann, Ye Ma, Manana Melikishvili, Steven Grason Godfrey, Zhuo Zhang, Kuey-Chu Chen, Eric C. Rouchka, and Yvonne N. Fondufe-Mittendorf

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Antioncogenic and Oncogenic Properties of Nrf2 in Arsenic-Induced Carcinogenesis, Young-Ok Son, Poyil Pratheeshkumar, Ram Vinod Roy, Andrew Hitron, Lei Wang, Sasidharan Padmaja Divya, Mei Xu, Jia Luo, Gang Chen, Zhuo Zhang, and Xianglin Shi

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Exogenous 17-β Estradiol Administration Blunts Progression of Established Angiotensin II-Induced Abdominal Aortic Aneurysms in Female Ovariectomized Mice, Sean E. Thatcher, Xuan Zhang, Shannon Woody, Yu Wang, Yasir Alsiraj, Richard Charnigo, Alan Daugherty, and Lisa A. Cassis

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Increasing Adipocyte Lipoprotein Lipase Improves Glucose Metabolism in High Fat Diet-Induced Obesity, R. Grace Walton, Beibei Zhu, Resat Unal, Michael Spencer, Manjula Sunkara, Andrew J. Morris, Richard Charnigo, Wendy S. Katz, Alan Daugherty, Deborah A. Howatt, Philip A. Kern, and Brian S. Finlin

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Activation of the NF-κB Pathway as a Mechanism of Alcohol Enhanced Progression and Metastasis of Human Hepatocellular Carcinoma, Fei Wang, Jin-Lian Yang, Ke-Ke Yu, Mei Xu, You-Zhi Xu, Li Chen, Yan-Min Lu, Hao-Shu Fang, Xin-Yi Wang, Zhong-Qian Hu, Fei-Fei Li, Lixin Kan, Jia Luo, and Si-Ying Wang

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Endoplasmic Reticulum Stress and Ethanol Neurotoxicity, Fanmuyi Yang and Jia Luo

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PACT/RAX Regulates the Migration of Cerebellar Granule Neurons in the Developing Cerebellum, Yue Yong, Ya Meng, Hanqing Ding, Zhiqin Fan, Yifen Tang, Chenghua Zhou, Jia Luo, and Zun-Ji Ke

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CD151-α3β1 Integrin Complexes are Prognostic Markers of Glioblastoma and Cooperate with EGFR to Drive Tumor Cell Motility and Invasion, Pengcheng Zhou, Sonia Erfani, Zeyi Liu, Changhe Jia, Yecang Chen, Bingwei Xu, Xinyu Deng, Jose E. Alfáro, Li Chen, Dana L. Napier, Michael Lu, Jian-An Huang, Chunming Liu, Olivier Thibault, Rosalind Segal, Binhua P. Zhou, Natasha Kyprianou, Craig Horbinski, and Xiuwei H. Yang

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Chaperone Hsp47 Drives Malignant Growth and Invasion by Modulating an ECM Gene Network, Jieqing Zhu, Gaofeng Xiong, Hanjiang Fu, B. Mark Evers, Binhua P. Zhou, and Ren Xu

Submissions from 2014

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CD151-α3β1 Integrin Complexes Suppress Ovarian Tumor Growth by Repressing Slug-Mediated EMT and Canonical Wnt Signaling, Lauren A. Baldwin, John T. Hoff, Jason Lefringhouse, Michael Zhang, Changhe Jia, Zeyi Liu, Sonia Erfani, Hongyan Jin, Mei Xu, Qing-Bai She, John R. Van Nagell Jr., Chi Wang, Li Chen, Rina Plattner, David M. Kaetzel, Jia Luo, Michael Lu, Dava West, Chunming Liu, Fred R. Ueland, Ronny Drapkin, Binhua P. Zhou, and Xiuwei H. Yang

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Aged rats are hypo-responsive to acute restraint: implications for psychosocial stress in aging, Heather M. Buechel, Jelena Popovic, Kendra Staggs, Katie L. Anderson, Olivier Thibault, and Eric M. Blalock

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Anti-Lysophosphatidic Acid Antibodies Improve Traumatic Brain Injury Outcomes, Peter J. Crack, Moses Zhang, Maria Cristina Morganti-Kossmann, Andrew J. Morris, Jonathan M. Wojciak, Jonathan K. Fleming, Ila Karve, David Wright, Maithili Sashindranath, Yona Goldshmit, Alison Conquest, Maria Daglas, Leigh A. Johnston, Robert L. Medcalf, Roger A. Sabbadini, and Alice Pébay

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Cardioprotection by Controlling Hyperamylinemia in a "Humanized" Diabetic Rat Model, Sanda Despa, Savita Sharma, Todd R. Harris, Hua Dong, Ning Li, Nipavan Chiamvimonvat, Heinrich Taegtmeyer, Kenneth B. Margulies, Bruce D. Hammock, and Florin Despa

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Comparative Analysis of Gingival Tissue Antigen Presentation Pathways in Ageing and Periodontitis, Octavio A. Gonzalez, Michael John Novak, Sreenatha S. Kirakodu, Luis Orraca, Kuey-Chu Chen, Arnold J. Stromberg, Janis Gonzalez-Martinez, and Jeffrey L. Ebersole

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Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers II: Sigma-2/PGRMC1 Receptors Mediate Abeta 42 Oligomer Binding and Synaptotoxicity, Nicholas J. Izzo, Jinbin Xu, Chenbo Zeng, Molly J. Kirk, Kelsie Mozzoni, Colleen Silky, Courtney Rehak, Raymond Yurko, Gary Look, Gilbert Rishton, Hank Safferstein, Carlos Cruchaga, Alison Goate, Michael A. Cahill, Ottavio Arancio, Robert H. Mach, Rolf Craven, Elizabeth Head, Harry LeVine III, Tara L. Spires-Jones, and Susan M. Catalano

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PKA-Mediated Phosphorylation of ATR Promotes Recruitment of XPA to UV-Induced DNA Damage, Stuart G. Jarrett, Erin M. Wolf Horrell, Perry A. Christian, Jillian C. Vanover, Mary C. Boulanger, Yue Zou, and John A. D’Orazio

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The Rak/Frk Tyrosine Kinase Associates With and Internalizes the Epidermal Growth Factor Receptor, Ling Jin and Rolf J. Craven