US Patent Number
5859311
Publication Date
1-12-1999
Abstract
Transgenic mice express increased levels of neurotrophin-3 (NT-3) in epithelium when their ancestors are microinjected with the NT-3 gene. The NT-3 growth factor expressing transgenic mice are useful in the study of neurodegenerative disorders of the brain such as Parkinson's syndrome and Alzheimer's disease, of the spinal cord motor neurons such as amyotrophic lateral sclerosis, and for testing drug candidates for the treatment of these diseases.
Assignees
University of Kentucky Research Foundation, Lexington, KY.
Application Number
534,685
Filing Date
11/27/1995
Recommended Citation
Albers, Kathryn M. and Davis, Brian M., "Transgenic Mice which Overexpress Neurotrophin-3 (NT-3) and Method of Use" (1999). Neuroscience Faculty Patents. 6.
https://uknowledge.uky.edu/neurobio_patents/6
