The composition of the intestinal microbiota has wide reaching effects on the health of an individual, including the development of protective innate immune responses. In this report, a fecal transplantation approach was used to determine whether resistance to food borne listeriosis was dependent on the murine gut microbiota. Transplantation of BALB/c/By feces did not increase the susceptibility of C57BL/6 mice to Listeria monocytogenes infection. Likewise, transplantation of C57BL/6 fecal matter did not enhance the resistance of BALB/c/By mice. Thus, intestinal microbiota composition is not a key factor that confers either susceptibility or resistance to food borne listeriosis in mice.
Digital Object Identifier (DOI)
Myers-Morales, Tanya; Bussell, Kate M.; and D'Orazio, Sarah E. F., "Fecal Transplantation does not Transfer Either Susceptibility or Resistance to Food Borne Listeriosis in C57BL/6 and BALB/c/By Mice" (2013). Microbiology, Immunology, and Molecular Genetics Faculty Publications. 28.