US Patent Number
7851172
Publication Date
12-14-2010
Abstract
A method for quantifying a neurodegenerative disorder in a patient that includes obtaining a fluid sample from the subject; measuring a protein biomarker complex in said fluid sample and correlating the measurement with mild cognitive impairment or Alzheimer's disease status. The biomarkers include those that comprise at least one of a transthyretin protein and/or a prostaglandin-H2 D-isomerase protein, and at least one second, different protein selected from a transthyretin, prostaglandin-H2 D-isomerase, beta-2-microglobulin, cystatin C, superoxide dismutase [Cu—Zn], plasma retinol-binding protein, phosphatidylethanolamine-binding protein, carbonic anhydrase 2, prostaglandin-H2 D-isomerase, and/or serotransferrin protein.
Assignees
University of Kentucky Research Foundation, Lexington, KY (US)
Application Number
11/459,793
Filing Date
07/25/2006
Recommended Citation
Lovell, Mark A. and Lynn, Bert C., "Biomarkers of Mild Cognitive Impairment and Alzheimer's Disease" (2010). Chemistry Faculty Patents. 7.
https://uknowledge.uky.edu/chemistry_patents/7
