US Patent Number
A method for diagnosing a neurological disease comprising detecting a neurological disease-specific biochemical marker macromolecule within a sample of extracted cerebral spinal fluid is disclosed. In particular, a radioactively labeled photoaffinity probe is used to diagnose a neurological disease. For instance, Alzheimer's disease can be diagnosed by detecting a disease-specific protein having a molecular weight of about 42,000 daltons, i.e., glutamine synthetase.
University of Kentucky Research Foundation, Lexington, Ky.
Haley, Boyd E., "Detection of Alzheimer's Disease and Other Diseases Using an Improved Photoaffinity Labeling Method" (1993). Chemistry Faculty Patents. Paper 32.