US Patent Number
A hydrogel microdome that can swell in response to a stimuli or target molecule is formed by polymerizing a mixture comprising a monomer capable of forming a hydrogel with a biopolymer. An array of hydrogel microdomes can be formed on a substrate by microspotting the mixture and polymerizing. The array can be used for high-throughput screening of analytes as well as for use as an actuator and biosensor using the swelling property of the hydrogel.
University of Kentucky Research Foundation, Lexington, KY (US)
Daunert, Sylvia; Deo, Sapna K.; Ehrick, Jason Douglas; Browning, Tyler William; and Bachas, Leonidas G., "Stimuli-Responsive Hydrogel Microdomes Integrated with Genetically Engineered Proteins for High-Throughput Screening of Pharmaceuticals" (2009). Chemistry Faculty Patents. Paper 10.