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Submissions from 2017

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C/D-Box SnoRNAs Form Methylating and Non-Methylating Ribonucleoprotein Complexes: Old Dogs Show New Tricks, Marina Falaleeva, Justin R. Welden, Marilyn J. Duncan, and Stefan Stamm

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Genetic Metabolic Complementation Establishes a Requirement for GDP-Fucose in Leishmania, Hongjie Guo, Natalia M. Novozhilova, Giulia Bandini, Salvatore J. Turco, Michael A. L. Ferguson, and Stephen M. Beverley

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Nuclear Spindles Pave the Way to Metastasis, Patrick J. Hensley and Natasha Kyprianou

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Serine-Dependent Sphingolipid Synthesis Is a Metabolic Liability of Aneuploid Cells, Sunyoung Hwang, H. Tobias Gustafsson, Ciara O’Sullivan, Gianna Bisceglia, Xinhe Huang, Christian Klose, Andrej Schevchenko, Robert C. Dickson, Paola Cavaliere, Noah Dephoure, and Eduardo M. Torres

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Fluorinated N,N'-Diarylureas as Novel Therapeutic Agents Against Cancer Stem Cells, Dasha E. Kenlan, Piotr G. Rychahou, Vitaliy M. Sviripa, Heidi L. Weiss, Chunming Liu, David S. Watt, and B. Mark Evers

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Clinical and Experimental Studies of a Novel P525R FUS Mutation in Amyotrophic Lateral Sclerosis, Lisha Kuang, Marisa Kamelgarn, Alexandra Arenas, Jozsef Gal, Deborah Taylor, Weiming Gong, Martin Brown, Daret St. Clair, Edward J. Kasarskis, and Haining Zhu

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Down Syndrome: Age-Dependence of PiB Binding in Postmortem Frontal Cortex Across the Lifespan, Harry LeVine III, H. Peter Spielmann, Sergey V. Matveev, Francesca Macchiavello Cauvi, M. Paul Murphy, Tina L. Beckett, Katie McCarty, Ira T. Lott, Eric Doran, Frederick A. Schmitt, and Elizabeth Head

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FBXW8-Dependent Degradation of MRFAP1 in Anaphase Controls Mitotic Cell Death, Duan-Zhuo Li, Shun-Fang Liu, Lan Zhu, Yu-Xing Wang, Yi-Xiang Chen, Jie Liu, Gang Hu, Xin Yu, Jian Li, Jin Zhang, Zhi-Xiang Wu, Han Lu, Wei Liu, and Bin Liu

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Nanoparticle Delivery of miR-34a Eradicates Long-Term-Cultured Breast Cancer Stem Cells via Targeting C22ORF28 Directly, Xiaoti Lin, Weiyu Chen, Fengqin Wei, Binhua P. Zhou, Mien-Chie Hung, and Xiaoming Xie

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Stabilization of the Transcription Factors Slug and Twist by the Deubiquitinase Dub3 is a Key Requirement for Tumor Metastasis, Yiwei Lin, Yu Wang, Qing Shi, Qian Yu, Cuicui Liu, Jing Feng, Jiong Deng, B. Mark Evers, Binhua P. Zhou, and Yadi Wu

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Latexin Inactivation Enhances Survival and Long-Term Engraftment of Hematopoietic Stem Cells and Expands the Entire Hematopoietic System in Mice, Yi Liu, Cuiping Zhang, Zhenyu Li, Chi Wang, Jianhang Jia, Tianyan Gao, Gerhard C. Hildebrandt, Daohong Zhou, Subbarao Bondada, Peng Ji, Daret K. St. Clair, Jinze Liu, Chang-Guo Zhan, Hartmut Geiger, Shuxia Wang, and Ying Liang

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TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia, Riadh Lobbardi, Jordan Pinder, Barbara Martinez-Pastor, Marina Theodorou, Jessica S. Blackburn, Brian J. Abraham, Yuka Namiki, Marc Mansour, Nouran S. Abdelfattah, Aleksey Molodtsov, Gabriela Alexe, Debra Toiber, Manon de Waard, Esha Jain, Myriam Boukhali, Mattia Lion, Deepak Bhere, Khalid Shah, Alejandro Gutierrez, Kimberly Stegmaier, Lewis B. Silverman, Ruslan I. Sadreyev, John M. Asara, Marjorie A. Oettinger, Wilhelm Haas, A. Thomas Look, Richard A. Young, Raul Mostoslavsky, Graham Dellaire, and David M. Langenau

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A Comparison of Nucleosome Organization in Drosophila Cell Lines, Rebecca L. Martin, John Maiorano, Greg J. Beitel, John F. Marko, Graham McVicker, and Yvonne N. Fondufe-Mittendorf

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Transcriptome-Wide Identification of the RNA-Binding Landscape of the Chromatin-Associated Protein PARP1 Reveals Functions in RNA Biogenesis, Manana Melikishvili, Julia H. Chariker, Eric C. Rouchka, and Yvonne N. Fondufe-Mittendorf

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Quaternary Interactions and Supercoiling Modulate the Cooperative DNA Binding of AGT, Manana Melikishvili and Michael G. Fried

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IGF-1 Mediated Neurogenesis Involves a Novel RIT1/Akt/Sox2 Cascade, Sajad Mir, Weikang Cai, Shaun W. Carlson, Kathryn E. Saatman, and Douglas A. Andres

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Mechanisms of Therapeutic Resistance in Prostate Cancer, Mary Nakazawa, Channing Paller, and Natasha Kyprianou

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Deficiency of KLF4 Compromises the Lung Function in an Acute Mouse Model of Allergic Asthma, Jeanette A. Nimpong, Wintana Gebregziabher, Udai P. Singh, Prakash Nagarkatti, Mitzi Nagarkatti, Johnie Hodge, Chunming Liu, Daping Fan, and Walden Ai

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Lipophosphoglycan Polymorphisms Do Not Affect Leishmania amazonensis Development in the Permissive Vectors Lutzomyia migonei and Lutzomyia longipalpis, Paula M. Nogueira, Agna C. Guimarães, Rafael R. Assis, Jovana Sadlova, Jitka Myskova, Katerina Pruzinova, Jana Hlavackova, Salvatore J. Turco, Ana C. Torrecilhas, Petr Volf, and Rodrigo P. Soares

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Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase, Warintra Pitsawong, Chad A. Haynes, Ronald L. Koder, David W. Rodgers, and Anne-Frances Miller

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Genome-Wide DNA Methylation Reprogramming in Response to Inorganic Arsenic Links Inhibition of CTCF Binding, DNMT Expression and Cellular Transformation, Matthew Rea, Meredith Eckstein, Rebekah Eleazer, Caroline Smith, and Yvonne N. Fondufe-Mittendorf

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The Molecular Mechanism of N-Acetylglucosamine Side-Chain Attachment to the Lancefield Group A Carbohydrate in Streptococcus pyogenes, Jeffrey Rush, Rebecca J. Edgar, Pan Deng, Jing Chen, Haining Zhu, Nina M. van Sorge, Andrew J. Morris, Konstantin V. Korotkov, and Natalia Korotkova

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What’s in a Name?, Michael D. Schaller, Gary McDowell, André Porter, Dorothy Shippen, Katherine L. Friedman, Matthew S. Gentry, Tricia R. Serio, and Wesley I. Sundquist

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Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New Classes of Antibacterial/Antifungal Agents, Sanjib K. Shrestha, Liliia M. Kril, Keith D. Green, Stefan Kwiatkowski, Vitaliy M. Sviripa, Justin Robert Nickell, Linda Phyliss Dwoskin, David S. Watt, and Sylvie Garneau-Tsodikova

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Peptide Inhibitors Targeting the Neisseria gonorrhoeae Pivotal Anaerobic Respiration Factor AniA, Aleksandra E. Sikora, Robert H. Mills, Jacob V. Weber, Adel Hamza, Bryan W. Passow, Andrew Romaine, Zachary A. Williamson, Robert W. Reed, Ryszard A. Zielke, and Konstantin V. Korotkov